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At Silence, our vision is to transform peoples’ lives around the world by silencing diseases through our precision engineered medicines and driving positive change for the communities around us.

Our investigational product candidates harness the body's natural mechanism of RNA interference (RNAi) to precisely target and silence disease-associated genes.

Learn How Gene Silencing Works

Our Clinical Trials

We are currently conducting clinical trials for cardiovascular disease due to high levels of lipoprotein(a), or Lp(a), and thalassemia.


Learn More About the APOLLO Phase 1 Clinical Program for Cardiovascular Disease Due to High Lp(a)

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Learn More About the GEMINI II Phase 1 Clinical Program for Thalassemia

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To support better understanding of the diseases we are currently researching, we have developed a series of ‘eBooks’ to provide an overview of their impact and current management approaches.