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At Silence, our vision is to transform peoples’ lives around the world by silencing diseases through our precision engineered medicines and driving positive change for the communities around us.

Our investigational product candidates harness the body's natural mechanism of RNA interference (RNAi) to precisely target and silence disease-associated genes.

Learn How Gene Silencing Works

We have updated the mindfulness coloring book below to support people living with Polycythemia Vera (PV) and their families. PV is a rare blood cancer that can have a major impact on a person’s quality of life. Techniques such as mindfulness, meditation and coloring can be used to reduce mental stress and promote relaxation whilst learning more about PV

Download the updated book here and help us spread awareness by sharing your artwork on social media. Use the hashtags #SilenceRareDisease #ShareYourColors, and don’t forget to tag Silence on LinkedIn and X and join our community in making a small difference to patients.

A special thank you to our partners, MPN Advocacy Network, MPN Alliance Australia, MPN Research Foundation and MPN Voice, for their input and collaboration.

Our Clinical Trials

We are currently conducting a clinical trial for polycythemia vera (PV)

SANRECO

Learn More About the SANRECO Phase 2 Study

Learn more

To support better understanding of the diseases we are currently researching, we have developed a series of ‘eBooks’ to provide an overview of their impact and current management approaches.