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Tag Archives: J Biol Chem

• Negative Regulation of the Acetyltransferase TIP60-p53 Interplay by UHRF1 (ubiquitin-like with PHD and RING finger domains 1).

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  May 18, 2013

  Related Articles Negative Regulation of the Acetyltransferase TIP60-p53 Interplay by UHRF1 (ubiquitin-like with PHD and RING finger domains 1). J Biol Chem. 2013 May 15; Authors: Dai C, Shi D, Gu W Abstract Numerous studies indicate the importance of acetylation in p53-mediated stress responses upon DNA damage. We and others... Contine Reading & Discuss→

• Sodium solute symporter and cadherin proteins act as Bacillus thuringiensis Cry3Ba toxin functional receptors in Tribolium castaneum.

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  May 08, 2013

  Related Articles Sodium solute symporter and cadherin proteins act as Bacillus thuringiensis Cry3Ba toxin functional receptors in Tribolium castaneum. J Biol Chem. 2013 May 3; Authors: Contreras E, Schoppmeier M, Real MD, Rausell C Abstract Understanding how Bacillus thuringiensis (Bt) toxins interact with proteins in the midgut of susceptible coleopteran... Contine Reading & Discuss→

• Molecular Identification and Characterization of an Essential Pyruvate Transporter from Trypanosoma brucei.

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  April 10, 2013

  Related Articles Molecular Identification and Characterization of an Essential Pyruvate Transporter from Trypanosoma brucei. J Biol Chem. 2013 Apr 8; Authors: Sanchez MA Abstract Pyruvate export is an essential physiological process for the bloodstream form of T. brucei as the parasite would otherwise accumulate this end product of glucose metabolism... Contine Reading & Discuss→

• Inhibition of isoleucyl-tRNA synthetase as a potential treatment for Human African Trypanosomiasis.

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  April 04, 2013

  Related Articles Inhibition of isoleucyl-tRNA synthetase as a potential treatment for Human African Trypanosomiasis. J Biol Chem. 2013 Apr 2; Authors: Cestari I, Stuart K Abstract Trypanosoma brucei sp. cause Human African Trypanosomiasis (HAT or African sleeping sickness). They initially proliferate in the hemolymphatic system, and then invade the central... Contine Reading & Discuss→

• Leucine rich repeat and Ig domain containing 1 (LINGO-1) promotes neuronal apoptosis by inhibiting with no lysine kinase 3 (WNK3) activity.

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  March 15, 2013

  Related Articles Leucine rich repeat and Ig domain containing 1 (LINGO-1) promotes neuronal apoptosis by inhibiting with no lysine kinase 3 (WNK3) activity. J Biol Chem. 2013 Mar 12; Authors: Zhang Z, Xu X, Xiang Z, Yu Z, Feng J, He C Abstract LINGO-1 is a functional component of the... Contine Reading & Discuss→

• Inhibition of nucleotide sugar transport in Trypanosoma brucei alters surface glycosylation.

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  March 01, 2013

  Inhibition of nucleotide sugar transport in Trypanosoma brucei alters surface glycosylation. J Biol Chem. 2013 Feb 26; Authors: Liu L, Xu YX, Caradonna KL, Kruzel EK, Burleigh BA, Bangs JD, Hirschberg CB Abstract Nucleotide sugar transporters (NSTs) are indispensible for the biosynthesis of glycoproteins by providing the nucleotide sugars needed... Contine Reading & Discuss→

• Protein Kinase D Promotes In Vitro Osteoclast Differentiation and Fusion.

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  February 24, 2013

  Protein Kinase D Promotes In Vitro Osteoclast Differentiation and Fusion. J Biol Chem. 2013 Feb 21; Authors: Mansky KC, Jensen ED, Davydova J, Yamamoto M, Gopalakrishnan R Abstract Although protein kinase D is broadly expressed and involved in numerous cellular processes, its function in osteoclasts has not been previously reported.... Contine Reading & Discuss→

• Integrin αPS3/βν-Mediated Phagocytosis of Apoptotic Cells and Bacteria in Drosophila.

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  February 23, 2013

  Integrin αPS3/βν-Mediated Phagocytosis of Apoptotic Cells and Bacteria in Drosophila. J Biol Chem. 2013 Feb 20; Authors: Nonaka S, Nagaosa K, Mori T, Shiratsuchi A, Nakanishi Y Abstract Integrins exert a variety of cellular functions as heterodimers of two transmembrane subunits named α and β. Integrin βν, a β-subunit of... Contine Reading & Discuss→

• Supervillin-mediated Suppression of p53 Enhances Cell Survival.

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  February 07, 2013

  Supervillin-mediated Suppression of p53 Enhances Cell Survival. J Biol Chem. 2013 Feb 4; Authors: Fang Z, Luna EJ Abstract Integrin-based adhesions promote cell survival, as well as cell motility and invasion. We show here that the adhesion regulatory protein supervillin increases cell survival by decreasing levels of the tumor suppressor... Contine Reading & Discuss→

• Identification of DDX6 as a cellular modulator of VEGF expression under hypoxia.

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  January 09, 2013

  Related Articles Identification of DDX6 as a cellular modulator of VEGF expression under hypoxia. J Biol Chem. 2013 Jan 4; Authors: de Vries S, Naarmann-de Vries IS, Urlaub H, Lue H, Bernhagen J, Ostareck DH, Ostareck-Lederer A Abstract Vascular endothelial growth factor A (VEGF) is a crucial proangiogenic factor, which... Contine Reading & Discuss→