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Tag Archives: Curr Biol

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  • Germ Cell Specification Requires Zygotic Mechanisms Rather Than Germ Plasm in a Basally Branching Insect.

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    April 30, 2013

    Germ Cell Specification Requires Zygotic Mechanisms Rather Than Germ Plasm in a Basally Branching Insect. Curr Biol. 2013 Apr 24; Authors: Ewen-Campen B, Donoughe S, Clarke DN, Extavour CG Abstract BACKGROUND: Primordial germ cell (PGC) specification is a universal process across animals, but the molecular mechanisms specifying PGCs are remarkably... Contine Reading & Discuss→

    Posted in :  News |  Other News |  Publications |  Syndicated |  Tagged in :  Curr Biol | 
  • The Microtubule-Binding Protein Ensconsin Is an Essential Cofactor of Kinesin-1.

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    February 13, 2013

    Related Articles The Microtubule-Binding Protein Ensconsin Is an Essential Cofactor of Kinesin-1. Curr Biol. 2013 Feb 5; Authors: Barlan K, Lu W, Gelfand VI Abstract Kinesin-1 is a major microtubule motor that drives transport of numerous cellular cargoes toward the plus ends of microtubules. In the cell, kinesin-1 exists primarily... Contine Reading & Discuss→

    Posted in :  News |  Other News |  Publications |  Syndicated |  Tagged in :  Curr Biol | 
  • Mechanism and Regulation of Cdc25/Twine Protein Destruction in Embryonic Cell-Cycle Remodeling.

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    January 09, 2013

    Related Articles Mechanism and Regulation of Cdc25/Twine Protein Destruction in Embryonic Cell-Cycle Remodeling. Curr Biol. 2012 Dec 31; Authors: Farrell JA, O'Farrell PH Abstract BACKGROUND: In Drosophila embryos, the midblastula transition (MBT) dramatically remodels the cell cycle during the 14(th) interphase. Before the MBT, each cycle is composed of only... Contine Reading & Discuss→

    Posted in :  News |  Other News |  Publications |  Syndicated |  Tagged in :  Curr Biol | 
  • Dendritic Filopodia, Ripped Pocket, NOMPC, and NMDARs Contribute to the Sense of Touch in Drosophila Larvae.

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    October 30, 2012

    Dendritic Filopodia, Ripped Pocket, NOMPC, and NMDARs Contribute to the Sense of Touch in Drosophila Larvae. Curr Biol. 2012 Oct 23; Authors: Tsubouchi A, Caldwell JC, Tracey WD Abstract BACKGROUND: Among the Aristotelian senses, the subcellular and molecular mechanisms involved in the sense of touch are the most poorly understood.... Contine Reading & Discuss→

    Posted in :  News |  Other News |  Publications |  Syndicated |  Tagged in :  Curr Biol | 
  • RNA Interference: Systemic RNAi SIDes with Endosomes.

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    October 28, 2012

    RNA Interference: Systemic RNAi SIDes with Endosomes. Curr Biol. 2012 Oct 23;22(20):R873-5 Authors: Rocheleau CE Abstract Systemic RNAi, the intercellular spreading of RNAi silencing, requires SID-1 and SID-3 to import silencing signals in Caenorhabditis elegans. How are these signals exported? SID-5, an endosome-associated protein, is a candidate for the job.... Contine Reading & Discuss→

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  • A Genome-wide Functional Screen Shows MAGI-1 Is an L1CAM-Dependent Stabilizer of Apical Junctions in C. elegans.

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    September 18, 2012

    A Genome-wide Functional Screen Shows MAGI-1 Is an L1CAM-Dependent Stabilizer of Apical Junctions in C. elegans. Curr Biol. 2012 Sep 11; Authors: Lynch AM, Grana T, Cox-Paulson E, Couthier A, Cameron M, Chin-Sang I, Pettitt J, Hardin J Abstract BACKGROUND: In multicellular organisms, cell-cell junctions are involved in many aspects of... Contine Reading & Discuss→

    Posted in :  News |  Other News |  Publications |  Syndicated |  Tagged in :  Curr Biol | 
  • SID-5 Is an Endosome-Associated Protein Required for Efficient Systemic RNAi in C. elegans.

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    SID-5 Is an Endosome-Associated Protein Required for Efficient Systemic RNAi in C. elegans. Curr Biol. 2012 Sep 11; Authors: Hinas A, Wright AJ, Hunter CP Abstract In the nematode C. elegans, RNAi silencing signals are efficiently taken up from the environment and transported between cells and tissues [1-3]. Previous studies implicating endosomal... Contine Reading & Discuss→

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  • Slicing-Independent RISC Activation Requires the Argonaute PAZ Domain.

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    July 18, 2012

    Related Articles Slicing-Independent RISC Activation Requires the Argonaute PAZ Domain. Curr Biol. 2012 Jul 10; Authors: Gu S, Jin L, Huang Y, Zhang F, Kay MA Abstract Small RNAs regulate genetic networks through a ribonucleoprotein complex called the RNA-induced silencing complex (RISC), which, in mammals, contains at its center one... Contine Reading & Discuss→

    Posted in :  News |  Other News |  Publications |  Syndicated |  Tagged in :  Curr Biol | 
  • Tropomodulin Protects α-Catenin-Dependent Junctional-Actin Networks under Stress during Epithelial Morphogenesis.

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    July 10, 2012

    Related Articles Tropomodulin Protects α-Catenin-Dependent Junctional-Actin Networks under Stress during Epithelial Morphogenesis. Curr Biol. 2012 Jul 3; Authors: Cox-Paulson EA, Walck-Shannon E, Lynch AM, Yamashiro S, Zaidel-Bar R, Eno CC, Ono S, Hardin J Abstract α-catenin is central to recruitment of actin networks to the cadherin-catenin complex [1, 2], but... Contine Reading & Discuss→

    Posted in :  News |  Other News |  Publications |  Syndicated |  Tagged in :  Curr Biol | 
  • Stonin 2 Is a Major Adaptor Protein for Clathrin-Mediated Synaptic Vesicle Retrieval.

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    June 26, 2012

    Related Articles Stonin 2 Is a Major Adaptor Protein for Clathrin-Mediated Synaptic Vesicle Retrieval. Curr Biol. 2012 Jun 20; Authors: Willox AK, Royle SJ Abstract At small synapses in the brain, clathrin-mediated endocytosis (CME) is the dominant mode of synaptic vesicle retrieval following weak stimulation [1-4]. Clathrin cannot bind to... Contine Reading & Discuss→

    Posted in :  News |  Other News |  Publications |  Syndicated |  Tagged in :  Curr Biol | 

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