News	Events
Publications	Companies
Clinical Trials

Tag Archives: Biochim Biophys Acta

• Formaldehyde induces hyperphosphorylation and polymerization of Tau protein both in vitro and in vivo.

  0 Replies
  

  May 02, 2013

  Formaldehyde induces hyperphosphorylation and polymerization of Tau protein both in vitro and in vivo. Biochim Biophys Acta. 2013 Apr 26; Authors: Lu J, Miao J, Su T, Liu Y, He R Abstract BACKGROUND: Chronic formaldehyde exposure leads to memory impairment and abnormal elevation of endogenous formaldehyde has been found in... Contine Reading & Discuss→

• Malfunctioning of adipocytes in obesity is linked to quantitative surfaceome changes.

  0 Replies
  

  April 16, 2013

  Related Articles Malfunctioning of adipocytes in obesity is linked to quantitative surfaceome changes. Biochim Biophys Acta. 2013 Apr 9; Authors: Moest H, Frei AP, Bhattacharya I, Geiger M, Wollscheid B, Wolfrum C Abstract Increased triglyceride accumulation in adipocytes caused by a misbalance between energy intake and energy consumption, results in... Contine Reading & Discuss→

• Mechanism of interleukin-1α transcriptional regulation of S100A9 in a human epidermal keratinocyte cell line.

  0 Replies
  

  April 09, 2013

  Related Articles Mechanism of interleukin-1α transcriptional regulation of S100A9 in a human epidermal keratinocyte cell line. Biochim Biophys Acta. 2013 Apr 3; Authors: Bando M, Zou X, Hiroshima Y, Kataoka M, Ross KF, Shinohara Y, Nagata T, Herzberg MC, Kido JI Abstract S100A9 is a calcium-binding protein and subunit of... Contine Reading & Discuss→

• X-Linked Intellectual Disability Gene CUL4B Targets Jab1/CSN5 for Degradation and Regulates Bone Morphogenetic Protein Signaling.

  0 Replies
  

  January 30, 2013

  Related Articles X-Linked Intellectual Disability Gene CUL4B Targets Jab1/CSN5 for Degradation and Regulates Bone Morphogenetic Protein Signaling. Biochim Biophys Acta. 2013 Jan 25; Authors: He F, Lu D, Jiang B, Wang Y, Liu Q, Liu Q, Shao C, Li X, Gong Y Abstract Cullin 4B (CUL4B) is a scaffold protein... Contine Reading & Discuss→

• Impairment of the proteasome is crucial for glucose-induced lifespan reduction in the mev-1 mutant of Caenorhabditis elegans.

  0 Replies
  

  January 29, 2013

  Related Articles Impairment of the proteasome is crucial for glucose-induced lifespan reduction in the mev-1 mutant of Caenorhabditis elegans. Biochim Biophys Acta. 2013 Jan 23; Authors: Fitzenberger E, Boll M, Wenzel U Abstract BACKGROUND: Hyperglycemia is a hallmark of diabetes that is associated with diabetic complications and a reduction of... Contine Reading & Discuss→

• The Ras-ERK MAPK regulatory network controls dedifferentiation in Caenorhabditis elegans germline.

  0 Replies
  

  July 24, 2012

  Related Articles The Ras-ERK MAPK regulatory network controls dedifferentiation in Caenorhabditis elegans germline. Biochim Biophys Acta. 2012 Jul 17; Authors: Cha DS, Datla US, Hollis SE, Kimble J, Lee MH Abstract How a committed cell can be reverted to an undifferentiated state is a central question in stem cell biology.... Contine Reading & Discuss→

• ERK1/2-dependent bestrophin-3 expression prevents ER-stress-induced cell death in renal epithelial cells by reducing CHOP.

  0 Replies
  

  June 20, 2012

  Related Articles ERK1/2-dependent bestrophin-3 expression prevents ER-stress-induced cell death in renal epithelial cells by reducing CHOP. Biochim Biophys Acta. 2012 Jun 12; Authors: Lee WK, Chakraborty PK, Roussa E, Wolff NA, Thévenod F Abstract Upon endoplasmic reticulum (ER) stress induction, cells endeavor to survive by engaging the adaptive stress response... Contine Reading & Discuss→

• Apoptosis-inducing factor (AIF) is targeted in IFN-α2a-induced Bid mediated apoptosis through Bak activation in ovarian cancer cells.

  0 Replies
  

  June 12, 2012

  Apoptosis-inducing factor (AIF) is targeted in IFN-α2a-induced Bid mediated apoptosis through Bak activation in ovarian cancer cells. Biochim Biophys Acta. 2012 Jun 6; Authors: Miyake K, Bekisz J, Zhao T, Clark C, Zoon KC Abstract Previously we have shown that interferon (IFN)-α induced apoptosis is predominantly mediated by the upregulation... Contine Reading & Discuss→

• De-ubiquitinating proteases USP2a and USP2c cause apoptosis by stabilising RIP1.

  0 Replies
  

  June 05, 2012

  De-ubiquitinating proteases USP2a and USP2c cause apoptosis by stabilising RIP1. Biochim Biophys Acta. 2012 May 29; Authors: Mahul-Mellier AL, Datler C, Pazarentzos E, Lin B, Chaisaklert W, Abuali G, Grimm S Abstract Dynamic ubiquitination impacts on the degradation of proteins by the proteasome as well as on their effects as... Contine Reading & Discuss→

• RNA interference targeting cytosolic NADP(+)-dependent isocitrate dehydrogenase exerts anti-obesity effect in vitro and in vivo.

  0 Replies
  

  May 01, 2012

  RNA interference targeting cytosolic NADP(+)-dependent isocitrate dehydrogenase exerts anti-obesity effect in vitro and in vivo. Biochim Biophys Acta. 2012 Apr 19; Authors: Nam WS, Park KM, Park JW Abstract A metabolic abnormality in lipid biosynthesis is frequently associated with obesity and hyperlipidemia. Nicotinamide adenine dinucleotide phosphate-oxidase (NADPH) is an essential... Contine Reading & Discuss→