Reports and Disclosures

In accordance with AIM Rule 26, Silence Therapeutics plc offers the following information:

Countries of Registration:

England and Wales

Company Registered Number:

2992058

Location of Operations:

Silence is headquartered in the U.K. with research and development operations carried out in Germany.

Nominated Advisors and Brokers:

N+1 Singer One Bartholomew Lane London EC2N 2AX Tel: +44 20 7496 3000

Constitutional Documents:

Disclosure Forms:

Meeting Notification and Proxy:

Annual and Interim Reports:

Recent Circulars:

Fundraising Presentations:

Committee Composition:

Remuneration Committee – Assisting the board in the discharging of its responsibilities related to remuneration of the company’s executive officers.

    • Jerry Randall
  • David Mack


Audit Committee – Assisting board oversight of accounting and financial reporting processes and the audits of the company’s financial statements

    • Jerry Randall (Chairman)
 

Nominations and Governance Committee – Recommending to the board those persons to be nominated for election as directors at any shareholders meeting

  • David Mack
 

Major Shareholdings

As at 10th August 2012 the Company had been informed of the following substantial interests of over 3% of the issued share capital of the Company:
Name Number Percentage of Issued Share Capital
Ora (Guernsey) Ltd. 330,000,000 22.51%
Robert Keith* 268,325,844 18.30%
Richard Griffiths 103,881,858 7,09%
Directors 80,620,000 5.50%
Charles Stanley, stockbrokers 61,122,880 4.17%
* includes an indirect position of 14.2m shares

Issued shares:

Number of securities in issue: 1,871,552,737 ordinary shares