Category Archives: Syndicated

The Arabidopsis RING E3 Ubiquitin Ligase AtAIRP3/LOG2 Participates in Positive Regulation of High Salt and Drought Stress Responses. Plant Physiol. 2013 May 21; Authors: Kim JH, Kim WT Abstract RING E3 ubiquitin (Ub) ligases have been implicated in cellular response to the stress hormone abscisic acid (ABA) as well as...

Tribbles 3 mediates endoplasmic reticulum stress-induced insulin resistance in skeletal muscle. Nat Commun. 2013;4:1871 Authors: Koh HJ, Toyoda T, Didesch MM, Lee MY, Sleeman MW, Kulkarni RN, Musi N, Hirshman MF, Goodyear LJ Abstract Endoplasmic reticulum stress has been linked to insulin resistance in multiple tissues but the role of...

A C-terminal truncated mutation of spr-3 gene extends lifespan in Caenorhabditis elegans. Acta Biochim Biophys Sin (Shanghai). 2013 May 21; Authors: Yang P, Sun R, Yao M, Chen W, Wang Z, Fei J Abstract The lifespan of Caenorhabditis elegans is determined by various genetic and environmental factors. In this paper,...

[Effects of class I( phosphatidylinositol-3-kinases inhibitor on gastric cancer cell xenografts in nude mice]. Zhonghua Wei Chang Wai Ke Za Zhi. 2013 May;16(5):484-8 Authors: Liu RL, Zhao K, Sun JL, Yu LY, Zhu BS, Yang XD, Xing CG Abstract OBJECTIVE: To investigate the effect of recombinant adenovirus (phosphatidylinositol-3-kinases(PI3K)(I()-RNAi-AD which blocks...

Servier selects third cardiovascular target triggering the first milestone under the collaborationSURESNES, France, and BOULDER, Colo., May 23, 2013 Servier, a privately-run French research-based pharmaceutical company and a major player in Europe and emerging markets having expertise in the development of treatments for cardiovascular diseases, and miRagen Therapeutics, Inc., a...

Related Articles A small cohort of FRUM and Engrailed-expressing neurons mediate successful copulation in Drosophila melanogaster. BMC Neurosci. 2013 May 21;14(1):57 Authors: Latham KL, Liu YS, Taylor BJ Abstract BACKGROUND: In Drosophila, male flies require the expression of the male-specific Fruitless protein (FRUM) within the developing pupal and adult nervous...

Related Articles Macrophage Migration and Invasion Is Regulated by MMP10 Expression. PLoS One. 2013;8(5):e63555 Authors: Murray MY, Birkland TP, Howe JD, Rowan AD, Fidock M, Parks WC, Gavrilovic J Abstract This study was designed to identify metalloproteinase determinants of macrophage migration and led to the specific hypothesis that matrix metalloproteinase...

Related Articles Smad3 regulates the diverse functions of rat granulosa cells relating to the FSHR/PKA signaling pathway. Reproduction. 2013 May 20; Authors: Xu J, Li Y, Yujie J, Liu Y, Shen C, Dong J Abstract The function of Smad3, a downstream signaling protein of TGF pathway, in ovarian follicle development...

Related Articles [Expression of long noncoding RNA MALAT1 gene in human nasopharyngeal carcinoma cell lines and its biological significance.] Nan Fang Yi Ke Da Xue Xue Bao. 2013 May 20;33(5):692-697 Authors: Xie LY, Hu ZY, Wang XY, Li ZG Abstract OBJECTIVE: To explore the expression of MALAT 1 in nasopharyngeal...

Related Articles Inhibiting cancer metastasis via targeting NAPDH oxidase 4. Biochem Pharmacol. 2013 May 17; Authors: Zhang B, Liu Z, Hu X Abstract Cancer metastasis is a major cause for cancer-related death and inhibiting cancer metastasis is an alternative way to treat cancer. Several lines of reported evidence suggest that...